A Secret Weapon For ceesdekker
A Secret Weapon For ceesdekker
Blog Article
‘Certainly, that is certainly about ideal. I hunt for a Actual physical understanding of biological devices inside a base-up way. I do think you may distinguish 3 strains of study in my team for the time being. The primary concerns chromosome construction: How does one obtain a metre-prolonged DNA polymer folded and organised in such a microscopic cell? We have now formulated visualisation techniques that allow us to study how, for instance, SMC proteins loop DNA (video clip on Youtube) in order to Make up chromosomes.
Springer Mother nature or its licensor retains special rights to this short article beneath a publishing arrangement While using the creator(s) or other rightsholder(s); author self-archiving on the approved manuscript version of this text is only governed through the terms of this kind of publishing agreement and applicable legislation.
Again in 1991, Sumio Iijima on the NEC Company had documented the synthesis of carbon nanotubes. Band framework calculations instructed that these nanotubes could show metallic band conduction. This could be a substantial benefit above the conducting polymers we experienced explored, which were being, in fact, disordered semiconductors providing simply variable-vary hopping conductivity.
Since 2000, Dekker has shifted the key concentration of his work in direction of biophysics where by he scientific tests the properties of single biomolecules and cells using the resources of nanotechnology. This modification of industry was driven by his fascination for your impressive performing of Organic molecular structures, along with with the extensive-term perspective that lots of appealing discoveries is usually expected With this industry.[five] Existing lines of analysis in his biophysics team are during the regions of:[six]
Your browser isn’t supported any more. Update it to have the very best YouTube encounter and our hottest capabilities. Learn more
Experimental stage diagram of negatively supercoiled DNA calculated by magnetic tweezers and fluorescence,
You're a Christian. If you could make such a synthetic mobile, would you be just one action nearer to God, or would the purpose of God have diminished somewhat yet again?
Nanopores signify a chic and versatile tool to measure single molecules. We investigation novel detection modes with reliable-state nanopores and several solutions to measure proteins with nanopores. Assignments encompass the subsequent:
2003, shown the main biosensors designed away from a carbon nanotube; settled the construction and mechanism of DNA repair service proteins; and discovery of a brand new technique for fabricating good-condition nanopores for DNA translocation
It had been all through this period that Dekker carried out study on magnetic spin programs and on sound in superconductors and semiconductors.
An integrated microfluidic platform for quantifying drug permeation across biomimetic vesicle membranes
Many new phenomena ended up identified, and he and his research team recognized a leading posture In this particular area of study. Dekker and his investigate group found out new physics of nanotubes along with explored the feasibility of molecular electronics. In 1998, they were the primary to build a transistor determined https://www.ceesdekker.net by a single nanotube molecule.
2005, discovery of your mechanism of DNA uncoiling by topoisomerase enzymes; discovery of very long-variety conformational improvements in Mre11/DNA repair complexes; and 1st drive measurements on the DNA molecule in a very nanopore
Ultimately, I will briefly sketch a number of our Concepts to examine the setting up of artificial cells, precisely our to start with steps to establish artificial mobile division.